Blood markers in mycosis fungoides and Sézary syndrome
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British Journal of DermatologyVolume 185, Issue 2 p. e38-e38 Plain Language SummaryFree Access Blood markers in mycosis fungoides and Sézary syndrome First published: 16 August 2021 https://doi.org/10.1111/bjd.20530AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text full-text accessPlease review our Terms Conditions Use check box below share version article.I have read accept the Wiley Online Library UseShareable LinkUse link a this article with your friends colleagues. Learn more.Copy URL Share linkShare onFacebookTwitterLinked InRedditWechat Abstract Linked Article: Dobos et al. Br J Dermatol 2021; 185:405–411. This study from Paris, France, looked at five substances (markers) blood see if they might help diagnosis (MF) (SS), types lymphoma (an immune system cancer) that affect skin. It can be difficult separate these conditions benign (non-cancerous) skin each other. Early MF, for example, may resemble eczema or psoriasis, whereas severe MF make red inflamed all over (a state known as erythroderma) – but erythroderma also occurs SS, psoriasis. Special tests are therefore routinely performed on samples try distinguish SS. In where there abnormal lymphocytes bloodstream, special samples. There is room improvement methods, hence research looking four previously reported possibly helpful SS advanced erythrodermic fifth useful early MF. The results 447 patients other lymphomas diseases, varying severity, showed three T-plastin, Twist KIR3DL2 might, combination, conditions, although not conditions. was hint predict relapse. remaining NKp46 Tox were less and, contrary previous reports, Volume185, Issue2August 2021Pages RelatedInformation
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Mycosis fungoides and Sézary syndrome.
Mycosis fungoides and Sézary syndrome are the most common of the cutaneous T-cell lymphomas, which are a heterogeneous group of neoplasms that affect the skin as a primary site. Although the aetiologies of mycosis fungoides and Sézary syndrome are unknown, important insights have been gained in the immunological and genetic perturbations that are associated with these diseases. Unlike some B-ce...
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By using flow cytometry with markers for CD3, CD4, CD26, and CD7, we examined the blood samples of 109 patients for abnormal T cells: 69 patients with mycosis fungoides (MF)/Sézary syndrome (SS), 31 hospitalized control subjects, and 9 patients with inflammatory skin disease. T cells were identified as quantitatively abnormal (>15% CD26- or CD7- T cells) or phenotypically abnormal (CD26- or CD7...
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Cutaneous T-cell lymphoma (CTCL) is an umbrella term that encompasses a group of neoplasms that have atypical T-lymphocytes in the skin. Mycosis fungoides (MF) is the most common type of CTCL and Sézary syndrome (SS) is the leukemic form. Treatment for CTCL is dependent on the stage of disease and response to previous therapy. Therapy is divided into skin-directed treatment, which tends to be f...
متن کاملHow I treat mycosis fungoides and Sézary syndrome.
The most common subtypes of primary cutaneous T-cell lymphomas are mycosis fungoides (MF) and Sézary syndrome (SS). The majority of patients have indolent disease; and given the incurable nature of MF/SS, management should focus on improving symptoms and cosmesis while limiting toxicity. Management of MF/SS should use a "stage-based" approach; treatment of early-stage disease (IA-IIA) typically...
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ژورنال
عنوان ژورنال: British Journal of Dermatology
سال: 2021
ISSN: ['1365-2133', '0007-0963']
DOI: https://doi.org/10.1111/bjd.20530